Clinical Translation of Quantitative MRI in MSK
Sunrise Course
ORGANIZERS: Margaret Hall-Craggs, Fang Liu
Monday, 05 June 2023
715A/B
07:00 -
08:00
Moderators: Valentina Mazzoli & Mikko Nissi
Skill Level: Intermediate to Advanced
Session Number: S-M-04
CME Credit
Session Number: S-M-04
Overview
This course offers an overview of quantitative MRI in musculoskeletal imaging. The speakers will summarize existing challenges in MSK imaging using qualitative MRI, introduce mostly investigated quantitative MRI techniques in MSK imaging, discuss the strengths and weaknesses of quantitative MRI, and finally introduce the Quantitative Imaging Biomarkers Alliance (QIBA) MSK initiative.
Target Audience
Radiologists, clinicians, technologists, and scientists interested in quantitative MRI applied in MSK imaging
Educational Objectives
As a result of attending this course, participants should be able to:
- Summarize the challenges of qualitative MRI in MSK imaging;
- Summarize the strengths and weaknesses of quantitative MRI in MSK imaging; and
- Explain the QIBA MSK initiative.
07:00 | | What are the current challenges with qualitative musculoskeletal magnetic resonance imaging? Marcelo Zibetti Keywords: Musculoskeletal: Cartilage, Musculoskeletal: Skeletal, Musculoskeletal: Tendons Qualitative MRI is still the
predominant MRI approach in musculoskeletal (MSK) applications. It has many advantages.
such as excellent soft-tissue contrast, submillimeter resolution, and the ability
to be quickly assessed by our visual system. However, qualitative MRI depends
on well-trained radiologists, and the reading of MRI can be subjective, and
differ from one reader to another due to several factors. In this talk, we will
briefly discuss some of the limitations of qualitative MRI in MSK applications,
including cartilage, bone, muscles, tendons, and ligaments. |
07:20 | | What Benefits can Quantitative MRI offer to MSK Imaging? Vladimir Juras Keywords: Musculoskeletal: Cartilage, Musculoskeletal: Joints Quantitative MRI
(qMRI) is a rapidly advancing field in musculoskeletal imaging that allows for
more accurate and objective assessment of tissue structure and composition.
QMRI techniques can provide measurements of parameters such as T1, T2, T1rho
and T2* relaxation times, magnetization transfer ratio (MTR), gagCEST, and diffusion
properties. These measurements can be used to detect subtle changes in tissue
microstructure. QMRI is particularly useful in evaluating degenerative cartilage
disease, bone health, and muscle function. The ability to quantify tissue
changes over time can also aid in monitoring disease progression and evaluating
the effectiveness of treatments. |
07:40 | | Update of RSNA QIBA MSK qMRI efforts Thomas Link Keywords: Musculoskeletal: Knee, Musculoskeletal: Joints, Musculoskeletal: Cartilage The
RSNA Quantitative Imaging Biomarker Alliance (QIBA) mechanism serves to
establish and standardize imaging biomarkers. To date there is only one
musculoskeletal QIBA committee that works on standardizing the application of
T1ρ and T2 imaging as biomarkers for the quantification of cartilage
composition. The committee has established claims for these biomarkers and
composed a profile which includes requirements and recommendations for MRI acquisition,
image analysis, participant handling, image quality assurance, and image
interpretation. Currently the QIBA MSK biomarker committee is in the process of
testing the profile to document clinical feasibility and assessing performance
at different imaging institutions. |