ISSN# 1545-4428 | Published date: 19 April, 2024
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At-A-Glance Session Detail
   
Cardiology for Physicists: Non-Ischemic Cardiomyopathy
Sunrise Course
ORGANIZERS: Michael Atalay, Teresa Correia, Tarique Hussain, Christopher Nguyen, Hajime Sakuma, Andrew Scott, Tobias Wech
Wednesday, 08 May 2024
Hall 606
07:00 -  08:00
Moderators: Kim-Lien Nguyen & Vlad Zaha
Skill Level: Basic
Session Number: S-W-05
CME Credit

Session Number: S-W-05

Overview
This course focusses on the clinical questions that cardiac MRI is commonly used to address. The course investigates the types and outcomes of heart diseases and describes the role of CMR in these conditions.

Target Audience
CMR physicists and engineers, particularly those starting out in cardiac imaging. Anyone else who has an interest, but little experience in cardiology.

Educational Objectives
As a result of attending this course, participants should be able to:
- Recall the objectives of cardiac imaging according to diagnosis.
- Describe clinical cardiology questions being addressed by CMR.
- Recall basic routine appropriate use criteria for cardiac MR.

07:00 Non-Ischemic Causes of Decreased Heart Function: Infiltrative Processes, Autoimmune Reactions, Inflammation & Drug Reactions
Tevfik Ismail

Keywords: Cardiovascular: Cardiovascular, Cardiovascular: Cardiac, Cardiovascular: Myocardium

Non-ischemic cardiomyopathies constitute a heterogeneous group of conditions characterized by morphological and functional ventricular abnormalities not due to coronary disease or its sequelae. Pragmatic classification of these disorders is based on observable morphofunctional traits (ventricular size, function, wall thickness, tissue characteristics, electrical abnormalities) and is combined with clinical, genetic, and laboratory/histopathologic data to arrive at a precise diagnosis. Inflammatory cardiomyopathies are defined as myocardial inflammation (myocarditis) associated with cardiac remodeling or dysfunction. Etiology has been crudely classified as “inherited” or “acquired”, however, it is increasingly recognized that conditions hitherto regarded as acquired can also have a genetic contribution or basis.
07:30What Can CMR Contribute to the Characterization of Non-Ischemic Cardiomyopathies?
Edythe Tham

Keywords: Cardiovascular: Cardiac, Cardiovascular: Cardiac function, Cardiovascular: Myocardium

CMR has developed beyond anatomical imaging to provide functional assessment and myocardial tissue characterization providing a powerful diagnostic tool in cardiomyopathies.  Fibrosis is the final common pathway of myocardial diseases from a variety of insults and is associated with declining ventricular function.  Late gadolinium enhancement can detect focal myocardial fibrosis; while T2 mapping (edema), T1 mapping and extracellular volume (diffuse fibrosis), provide quantitative parameters that are used in the diagnosis, management and follow up of patients with non-ischemic cardiomyopathies.  A shift towards these imaging parameters should provide a non-invasive serial marker to assess response to treatments and may predict outcome.