ISSN# 1545-4428 | Published date: 19 April, 2024
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At-A-Glance Session Detail
   
Pulse Sequence Design
Weekend Course
ORGANIZERS: Rita Nunes, Dan Ma, Yarach Uten
Sunday, 05 May 2024
Nicoll 2
07:45 -  11:45
Moderators: Yong Chen & Nan Wang
Skill Level: Basic to Intermediate
Session Number: WE-20
CME Credit

Session Number: WE-20

Overview
This course describes the basic principles for the generation of the MRI signal/contrasts and their corresponding spatial encoding together with the broad categories of pulse sequences. Ultimate encoding techniques, including B0 encoding, RF encoding, and non-linear gradients will be also described. Challenges and opportunities in MR-guided interventions and AI-based sequence design will be presented. This course also overviews available open-source software tools developed to facilitate MR pulse sequence design.

Target Audience
MRI Physicists and engineers interested in understanding and implementing MRI pulse sequences and clinicians interested in learning the basic features and properties of common MRI pulse sequences.

Educational Objectives
As a result of attending this course, participants should be able to:
- Explain the fundamental concepts related to the generation and spatial encoding of the MRI signal;
- Describe various pulse sequences and encoding techniques for acquiring MRI data; and
- Describe the roles of AI in pulse sequence design.

07:45Basic MR Acquisition Walkthrough
Sung-Hong Park

Keywords: Image acquisition: Sequences

MRI involves the sequential application of pulsing in RF and gradient coils, known as pulse sequences. This talk aims to explain fundamental concepts on how the gradient and RF pulsing generates an MR image. It covers the mathematical perspective of Fourier transform and the relation between the integral area of the gradient pulsing and the position in k-space. The presentation describes the combined utilization of RF and gradient pulsing for generating tomographic images, elucidating the role of a k-space trajectory in image formation. Key concepts such as slice selection, frequency encoding, phase encoding, and k-space will be explored.
08:15 Imaging Acceleration Techniques
Hua Guo

Keywords: Image acquisition: Fast imaging, Image acquisition: Sequences, Image acquisition: Reconstruction

Since the advent of MRI technology, image acquisition acceleration has consistently been one of the most prominent research topics in the field. Up to now, sampling acceleration still remains a central focus in MR technology research. Numerous acceleration techniques have been developed, with some already incorporated into products. These techniques include fast imaging sequences, partial Fourier-encoding, parallel imaging, compressed sensing, deep learning, and combinations thereof. Imaging acceleration techniques are widely used in anatomical, functional, and dynamic imaging. This lecture will provide a brief explanation of the fundamental principles behind some of these techniques.
08:45 Open-Source Pulse Sequence Design & Simulation
Maxim Zaitsev
09:15 Break & Meet the Teachers
09:45 Pulse Sequence Design for MR-Guided Interventions
Adrienne Campbell-Washburn

Keywords: Image acquisition: Sequences, Physics & Engineering: Interventional

During an MR-guided intervention, an invasive procedure is performed while the patient is inside the MRI system, and image guidance is used for real-time device navigation or to assess the therapeutic progress. The workflow for MRI-guided interventions differs from typical diagnostic MRI, and these procedures are more demanding on image acquisition and reconstruction times. Therefore, pulse sequences are designed differently. This talk will describe: interactive real-time imaging to enable the navigation of devices through complex anatomy, sequences to visualize interventional devices, thermometry methods to monitor thermal interventions, tracking motion for MRI-guided radiotherapy, and sequence compatibility with low-latency reconstruction.
10:15 Filling the Gap Between Innovative Sequence Design & Clinical Practice
Jeanette Schulz-Menger
10:45 AI-driven pulse sequence design
Ricardo Otazo

Keywords: Image acquisition: Sequences, Image acquisition: Machine learning

Artificial intelligence (AI) provides new tools to solve complex optimization problems, such MRI pulse sequence design. AI can be used to efficiently design the RF pulses and gradient waveforms to achieve the required image contrast and k-space trajectory or to optimize the schedule of acquisition parameters in MR fingerprinting, according to hardware constraints such as gradient amplitude and slew rate. This lecture will review techniques that use AI to design MRI pulse sequences such as AutoSeq, MRZero, and optimization of parameter schedule for MR fingerprinting. The application of ChatGPT for auto-generation of pulse sequence code will be also discussed.   
11:15 Ultimate MR Encoding
Lars Kasper