Advances in Perinatal MRI
Weekend Course
ORGANIZERS: Emmanuel Barbier, Jonathan Dillman, Christian Federau, Dan Wu
Sunday, 05 May 2024
Nicoll 1
07:45 -
11:35
Moderators:
Fetal MRI: Su-zhen Dong & Jana Hutter
Infant MRI: Sean Deoni & Peiying Liu
Skill Level: Basic to Advanced
Session Number: WE-22
CME Credit
Session Number: WE-22
Overview
This educational session focuses on both basic MRI techniques and recent advances in perinatal (fetal and infant MRI). The topics will cover acquisition and analysis techniques, safety issues in this special population, challenges with motion, etc. We will also discuss the clinical and basic science applications of perinatal MRI, including normal development and perinatal diseases associated with the brain and body organs.
Target Audience
MR physicists, obstetricians, neonatologists, and pediatric radiologists.
Educational Objectives
As a result of attending this course, participants should be able to:
- Define basic techniques in fetal and infant MRI;
-Summarize the new development in the field; and
- Describe what perinatal MRI can do to help in clinical settings.
| Fetal MRI |
07:45 | | Fetal Brain Acquisition & Analysis Joseph Hajnal |
08:10 |  | Normal Fetal Brain Development & Prenatal Diseases Guangbin Wang Keywords: Cross-organ: Antenatal, Neuro: Brain, Education Committee: Clinical MRI The most rapid growth of the brain occurs in utero. MRI demonstrates the major developmental processes in utero, including the proliferation, migration, organization , gyration and myelination. Awareness of normal fetal brain development contributes to identify abnormalities. The key points for the MRI features of the common abnormalities promote accurate prenatal diagnosis. In our talk, we present the key signs of ventriculomegaly, callosal agenesis, microcephaly, schizencephaly, gray matter heterotopia, holoprosencephaly, intra/extra-cerebral hemorrhage and posterior fossa anomalies. |
08:35 | | Fetal-Placental Interactions Yao Wu |
09:00 | | Safety Issues in Fetal MRI Teresa Victoria |
09:25 | | Break & Meet the Teachers |
| Infant MRI |
09:55 |  | Infant MRI Acquisition & Safety Issues Jian Yang, Xianjun Li, Chao Jin Keywords: Cross-organ: Neonatal, Image acquisition: Motion correction, Cross-organ: Development Infant MRI is challenging due to their immaturity, small physical size, and motion artifact. A customized approach tailored to each baby's age and functional status with appropriate combination of dedicated procedure, imaging hardware and software is key. This presentation summarizes several technical and clinical approaches that can help to ensure safety and decrease the need for sedation in infants. These range from feeding and swaddling to specialized small bore scanners and coils, MRI compatible incubators, and noise-reduction methods. New pre- and post-processing techniques with artificial intelligence can also decrease both scan time and motion artifacts to enable a successful scan. |
10:20 |  | Why Big Tools for Small Brains Pew-Thian Yap Keywords: Neuro: Brain The infant brain is not a miniaturized adult brain and undergoes rapid and unique developmental processes. Using computational tools meant for adult MRI to analyze infant brains often leads to subpar results. This presentation discusses resources tailored specifically for analyzing infant MRI across various modalities, aiming to provide clearer insights into early human brain development. |
10:45 | | Normal & Abnormal Infant Brain Development Yong He Keywords: Neuro: Brain connectivity The structure and function human brain undergo rapid reorganization from birth to infancy, laying a critical foundation for the establishment of extensive cognitive and behavioral abilities later in life. I will present recent advances in typical and atypical brain development during infancy using multimodal neuroimaging techniques and connectome-based approaches. |
11:10 |  | Infant MRI Applications Beyond the Brain Yun Peng Keywords: Education Committee: Clinical MRI The applications of infant MRI have extended beyond the realm of brain imaging. This lecture will elaborate on the significance of MRI in infant imaging, elucidate the challenges inherent in such imaging endeavors. We address clinical inquir, andies concerning the fundamental concepts essential for acquiring optimal images and deepen the understanding of the distinctive and optimal workflows associated with infant MR imaging. Moreover, we endeavor to present a large number of clinical cases beyond brain imaging, serving to illustrate the extensive applicability of infant MR examination in clinical settings and foster a deeper comprehension of this topic. |