Now, in Some Time or Never: Is This Ready To Go Clinical? Neurofluids
Sunrise Course
ORGANIZERS: Seung Hong Choi, Harpreet Hyare, Christin Sander, Katharina Schregel, Wietske van der Zwaag
Tuesday, 13 May 2025
311
07:00 -
08:00
Moderators: Shinji Naganawa & Toshiaki Taoka
Skill Level: Basic to Intermediate
Session Number: S-T-05
No CME/CE Credit
Session Number: S-T-05
Overview
Advanced MRI methods to assess neurofluid flow and dynamics or proteins and metabolites are emerging and scientifically well investigated. Moreover, techniques to dramatically speed up image acquisition were developed. However, are these scientific achievements ready for the clinical routine? Which advancement is really needed for patient care? Will a novel technique make the clinician's life easier or just more complicated?
Target Audience
Neuroscientists, neuroradiologists, clinicians who currently explore new MRI techniques, and MR physicists and engineers developing new MRI methodologies.
Clinicians in search of a solution to a specific clinical problem, scientists that want to know if a specific application is transferable to the clinical routine soon, in the hopefully near future or at all.
Educational Objectives
As a result of attending this course, participants should be able to:
• Describe methods to image neurofluids;
• Identify fast imaging techniques that are applicable in the clinical routine; and
• Interpret the results from CEST-imaging in the context of brain diseases.
| 07:00 | | Ways to Image Neurofluids Lynne Bilston Keywords: Neuro: Brain, Neuro: Spinal cord The neurofluid system encompasses both CSF and fluids within the brain and spinal cord. MRI can provide insights into how these fluids move physiologically as well as their role in neurological disorders. Both invasive and non-invasive techniques have a role to play. Phase-contrast imaging is useful for quantifying bulk CSF flow, and can be gated to the cardiac cycle or real-time. Diffusion weighted techniques, including IVIM and DTI-APLS, can provide information on intraparenchymal fluid behaviour. Gd contrast methods provide the most definitive data on transport from the CSF into the parenchyma and clearance. |
| 07:30 | | Which Neurofluids Do I Need To Image in My Patients? Junko Kikuta |